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The Secrets of The Endocannabinoid System


Article by Insider Story by

One of the most important systems in our bodies is often overlooked until more recently. The Endocannabinoid system is involved in establishing and helping to maintain homeostasis within the human body. Cannabinoids and their receptors can be found in all parts of an animals’ body from the brain, tissues, glands and immunity cells. For example, a life process called autophagy; the process in which cells isolate part of their contents to be recycled, happens with the help of this system. The cannabinoid system also assists in the communications between cells and other bodily systems.

Cannabinoids are substances in our body used to stimulate the Endocannabinoid system. Two molecules are found naturally in the human body, anandamide (the first cannabinoid receptor to be discovered) and 2-arachidonoylgylcerol (2-AG ), found mostly in the nervous system as well as human milk. Similar substances we find in plants, they are known better at delta-9-tetrahydrocannbinol (THC) as well as CBD and CBN. It is now being thought by scientists throughout the world that these substances are the co-creators of. Assisting in all aspects from conception, implantation, embryo growth, birth as well as nursing from our mothers, perhaps this is true.

There is also a receptor that a cannabinoid will bind to stimulating a child’s

knowledge to suckle from its mother …

Life is not possible if we are deprived of such natural substances. Starting with conception, both CB1 and CB2 receptors are found on the sperm cells. Levels of the cannabinoid AEA are needed to control the viability and mobility of the sperm. Both Anandamide and 2-AG are found in a woman’s uterus. These substances are essential for successful passage through the fallopian tubes and implantation into the womb. There is also a receptor that a cannabinoid will bind to; stimulating a child’s knowledge to suckle from its mother, making sure the child receives cannabinoids that will help strengthen their immune systems.

Dr. Dreher from Jamaica conducted many studies of pregnant woman who ingested cannabis from tea as well as smoking. He noted in the first few days of life, there were no positive or negative neurological effects; however, there was a great difference between the two types of children in the first month of life. He notes, “…The exposed babies showed better physiological stability, required less examiner facilitation to reach an organized state and become available for social stimulation”. Several years later the children were brought back and there was no difference in developmental testing between the two groups. Later Dreher studied the rate of infant mortality. He took just under 3,000 children and divided them between those with no cannabis in their systems and those who did. Those who were drug negative had an average mortality rate of 15, 7 per 1000 while the other group was significantly lower rate of only 8, 9 deaths per 1000.

More recently, Biotrial started a study at the Hospital of Rennes in France. Instead of using the natural cannabis plant, they created a synthetic drug. This was known as BIA 10-2427 (fatty acid amide hydrolase inhibitor. Basically this synthetic drug was used to block the necessary process that happens within the human endocannabinoid system. After 3 days on the trial drug 5 patients were hospitalized, one died as he was determine brain dead and the other 4 are expected to suffer from permanent neurological damage that is irreversible.

There are numerous studies, articles, and information available to the general population, it is up to us to increase our own knowledge, the resources are there, we must educate ourselves.

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